Officials say one person drowned and one person is missing in Indiana flooding.
21 of the state's 92 counties have been declared disaster areas.
In Seymour, a rising White River has forced officials in the southern Indiana city to evacuate several neighborhoods.
Seymour Mayor Craig Luedeman says water that has been rising quickly since 6 a.m. Sunday forced the mandatory evacuation of more than 100 homes. Firefighters and police set up an emergency command post and are helping with the order.
Rain up to 10 inches drenched south-central Indiana Saturday, triggering flooding and evacuations in several areas.
Some of that high water has started to move farther south, heading toward the Ohio River. National Weather Service hydrologist Al Shipe says some parts of the state could see flooding that approaches record levels set in 1913.
Indiana State Police say two major north-south highways have reopened after being shut down for about a day because of the flooding.
Sergeant Donald Gregory says Interstate 65 from Indianapolis to Louisville, Kentucky, and U.S. 31 north and south of Columbus are open.
Police are still requesting that people limit their travel in Columbus because of the flooding.
He says rescue efforts in Jackson County are being hampered by an enormous call volume requesting road openings.
He asks that people only call for emergencies.