Markisha Wright scored 20 points for No. 5 Notre Dame in a 128-55 romp past St. Francis, Pa., on Monday.
Notre Dame (10-1) dominated on both ends of the floor, forcing 33 turnovers and turning those into 49 points. The Irish led 63-25 at the break, their largest halftime lead of the season.
Alexa Hayward led the Red Flash (5-6) with 13 points.
Natalie Achonwa and Kayla McBride made easy shots from the low post for Notre Dame, many off give-and-gos from point guard Skylar Diggins.
Notre Dame coach Muffet McGraw had her reserves, including Wright, in the game with 13 minutes to play in the first half.
It was the final pre-Big East tune-up for the Irish before their conference opener Jan. 5 at No. 1 Connecticut.