Jerian Grant scored 19 points on Monday night, and 17th-ranked Notre Dame used its patient offense to get open shots for a 66-60 victory that extended No. 21 Cincinnati's home-court misery.
Notre Dame (14-1, 2-0 Big East) has won 12 in a row for the first time since 2006-07. It's the best start during coach Mike Brey's 13 seasons.
The Fighting Irish did it their way, passing for open shots on the perimeter and spreading out a defense that has been Cincinnati's strength.
Cincinnati (13-3, 1-2) wore new, all-black uniforms - Notre Dame wore white - for a home game that took on extra significance. The Bearcats opened the season 12-0, but have lost three of their last four, falling at home to New Mexico, St. John's and Notre Dame.
It's their longest home losing streak since 2006-07, coach Mick Cronin's first season picking up the pieces from coach Bob Huggins' ouster.