Brook Lopez scored 25 points and Brooklyn opened overtime on a 9-3 run to pull away from Indiana 89-84 on Monday night.
The Nets (30-22) ended a five-game losing streak at Bankers Life Fieldhouse and won for just the second time in games overall despite playing without injured guard Deron Williams.
Indiana (31-21) lost its second straight home game in overtime, the losses coming on the heels of a 15-game home winning streak. George Hill scored 22 points and Roy Hibbert added 12 on a night the Pacers shot just 34.4 percent from the field and All-Star Paul George finished with five points.
The Pacers appeared to swing the game with a 7-0 run that gave them a 76-72 lead with 1:38 left in regulation.
But Brooklyn scored the final four points to force overtime and started fast in the extra period to put away the game.