Jason Donald singled home the winning run with two outs in the 12th inning, lifting the Cleveland Indians over the Chicago White Sox 4-3 on Tuesday night.
Lonnie Chisenhall doubled with one out against Matt Thornton (4-10), who then intentionally walked Russ Canzler.
Right-hander Nate Jones came on to face announced pinch hitter Matt LaPorta, who was then replaced by lefty swinging Jack Hannahan. Jones struck him out before Donald hit a liner into the left-field corner.
Chris Seddon (1-1) pitched a scoreless 12th for the win, Cleveland's seventh in 17 meetings with Chicago. It was the left-hander's first victory since July 24, 2010, when he was with Seattle.