Charel Allen had 22 points and 11 rebounds and No. 16 Notre Dame pulled away from No. 21 Syracuse in the final 3 minutes for a 79-67 victory on Saturday night, the fifth straight win for the Irish.
Playing the first of a three-game road trip, Notre Dame (20-5, 8-3 Big East) moved to 17-0 in Big East play against Syracuse (19-5, 7-4) and into a tie for fourth in the conference with Pittsburgh.
Erica Williamson had 14 points and 11 rebounds and Lindsay Shrader had 12 points for the Irish, who won last season's meeting with Syracuse 83-55.
Erica Morrow led the Orange with 19 points, Nicole Michael had 14 points and six rebounds, and Vaida Sipaviciute had 12 points. Chandrea Jones, the team's leading scorer at 16 points, finished with just four on 1-for-12 shooting.