Mike Brey's Irish will shoot for the 33rd straight home win and 14th consecutive against Big East opponents when they host rival DePaul Saturday at 6pm at the Joyce Center.
It will be the 97th meeting between the two schools.
Notre Dame has won two straight games, including an 81-74 overtime victory over Providence on Thursday. Luke Harangody scored a career high 31 in the game.
The Irish are 15-4 and 5-2 in the Big East. They are currently in 2nd place in the conference standings, but just a half-game ahead of five teams.
DePaul is just 9-11 overall but 4-4 in the Big East. The Blue Demons have lost two straight games, including a 60-55 loss to Syracuse in their last game.
This will be the first of two meetings this season between the Irish and Blue Demons. The two will battle at DePaul on March 2nd.
Notre Dame leads the all-time series 52-44. DePaul has not won at the Joyce Center since 1994.
Following Saturday's game, the Irish head to the road to face Seton Hall next Wednesday.