South Bend Fire responded to a house fire just after 5 a.m. in the 1600 block of South Michigan Street, across from Family Dollar.
Michigan was blocked off at Indiana Avenue for several hours while firemen doused the flames. Two ladder trucks were on the scene.
Only northbound traffic was affected because Michigan is a one-way at that point.
Neighbors say the house was vacant, and it does not appear that anyone was inside or that anyone was injured.