New Tourette's Treatment Quiets Tics

Blinking and grunting are just some of the uncontrollable twitches and sounds kids with Tourette’s make. The involuntary movements and sounds impact a child's ability to learn and socialize at school.

Now, an investigational drug is helping them live with their disease.

Henry D'Alessio got his first guitar four years ago. It was the same year he was diagnosed with Tourette’s.

"My neck kept going back and forth," said Henry.

"And these movements were so intense and there were so many of them, if you were stopped at a stop light, the car would actually move," explains Henry’s Mom Daeinka D’Alessio.

Henry takes medication to help control it, but it has also caused him to gain 60 pounds in two years. It is a common side effect of current meds.

"A lot of weight gain and sometimes the emergence of other involuntary movements, sometimes cardiac problems, sleepiness and fatigue," explains Katie Kompoliti an Associate Professor of Neurological Sciences at Rush University Medical Center.

Now, a new investigational drug used to treat schizophrenia and depression could treat the disorder with fewer side effects.

"It is going to work for tics because it blocks dopamine," says Kompoliti.

It's the first Tourette’s drug available in pill form. And Henry has to remember to take his meds twice a day.

"It would make life a lot easier because I would not have to keep track of that all the time," says Henry.

Instead he would have more time to make music.

As of now, there is no cure for Tourette’s. The phase three trial of this new pill is currently recruiting kids with Tourette’s in 100 centers around the world.


TOPIC: New Tourette's Treatment Quiets Tics
REPORT: MB # 3688

BACKGROUND: Tourette's syndrome (TS) is caused by a malfunction in the brain and can be linked to genetics. Adults and children who are affected by this syndrome experience "tics" which are uncontrollable movements and sounds. It is common for Tourette's patients to have other issues such as OCD, ADHD, anxiety, emotion and behavior control problems and learning difficulties. TS is measured by the severity of the patient's tics; sometimes a patient's tics will go away by the time they have reached adulthood. (Source:
SYMPTOMS: If a person is under the age of 18 and is noticing constant tics for more than a year, then there may be a chance that the individual has Tourette's syndrome. There are two kinds of motor tics and two kinds of vocal tics; simple and complex tics. Simple motor tics include: head jerking, eye darting and blinking, finger flexing and shoulder shrugging. Complex motor tics consist of flapping the arms, hopping around and crude gesturing. As for vocal tics, some simple symptoms are yelling, hiccupping and throat clearing, while complex vocal tics incorporate the repetition of another's own words, the use of different tones of voice and the use of swear words. (Source:
TREATMENT: As of now, there is no cure for Tourette's syndrome, but there are medications offered to those who have tics that interfere with daily functioning. Most patients do not need treatment but behavioral treatments such as habit reversal and comprehensive behavioral intervention for tics (CBIT) are offered to those who suffer from severe tics. (Source:
NEW TREATMENT: A new drug is being studied to decrease the amount of tics a patient with Tourette's experiences. Typical medication is injected into a muscle several times a day to relieve the tic, while this new pill only requires one dose a week. Side effects from older medication include weight gain, fatigue and dulling of the mind. This new medication is still being studied but will be preferred for patients so they do not have to constantly remember to take their medicine. (Source:

Lucy Blasucci, RN,
Research Coordinator
Rush University Medical Center

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at

Comments are posted from viewers like you and do not always reflect the views of this station.
powered by Disqus
WNDU - Channel 16 54516 State Road 933 South Bend, IN 46637 Front Desk: 574-284-3000 Newsroom: 574-284-3016 Email:
Copyright © 2002-2014 - Designed by Gray Digital Media - Powered by Clickability 228222671 -
Gray Television, Inc.