Indiana State Police say all the lanes of the Indiana Toll Road are open, between mile marker 96 and 100, and traffic is flowing. The westbound lanes were closed while crews cleaned up after a series of accidents early Tuesday morning.

Police say a pickup truck collided with a semi at mile marker 100, near Bristol, around 4:45 a.m. Tuesday. The pickup rolled over and two people suffered serious injuries. They were airlifted from the scene.

Soon after an Indiana State Trooper who was responding to the accident lost control of his vehicle, crashed into a guard rail and struck an Indiana Toll Road maintenance vehicle. No one was hurt in the accident.

Around 5:15 a tractor-trailer struck another semi that was stopped due to the first accident. When the vehicles collided one exploded and both burst into flames. One man was airlifted with serious burns.